Opioids and sedatives have dangers even when not coupled with other substances.
Marijuana with blood thinners are another potentially deadly combination. Marijuana might cause blood thinners to perform too well, which can be harmful.
Anxiety and depression treatments can have unpleasant and even hazardous effects when taken with marijuana.
SSRIs (like Cipralex or Prozac) and Benzodiazepines (like Xanax or Valium) can both have deleterious effects when taken with marijuana.
Tamoxifen, a medicine used to fight breast cancer, may lose its effectiveness when used with marijuana.
While the drugs we listed above could be hazardous or risky when taken with marijuana, more research is needed.